Contract # 36F79719D0049
Axolotl Cryo™ is a cryopreserved liquid allograft derived from the placental components of the amnion to advance soft tissue repair, replacement, and reconstruction. It is classified as minimally manipulated under FDA regulation 21 CFR Part 1271 and section 361 of the PHS.
The two primary cell lines which reside in the amnion are human mesenchymal stromal cells (hMSC) and human amnion epithelial cells (hAEC). Both of these cells are considered to be pluripotent stem cells. Axolotl Cryo™ contains growth factors and cytokines such as epidermal growth factor (EGF), vascular endothelial growth factor (VEGF),and transforming growth factor – beta (TGF-ß),Interleukin-10 (IL-10). These proteins are essential for fetal growth and development and express significant therapeutic benefits when used as a treatment to stimulate repair and regeneration. Axolotl Cryo™ is immune-privileged, anti-inflammatory, anti-fibrotic, pro-vascular, and cytoprotective because of the cells being sourced from the amnion. These secreted factors also signal endogenous progenitor cells to promote regeneration and repair of damaged or degenerated tissue.
• Human allograft under FDA regulation 21 CFR Part 1271 and section 361 of the PHS
• Immune privileged with anti-inflammatory and anti-bacterial properties
• A rich source of growth factors, proteins, cytokines, hyaluronic acid, and collagen scaffolds
• Contains extracellular matrix components for cellular attachment and proliferation
• Cryopreserved for an extended shelf life
• Ease of use
Our tissue is recovered from living donors that are tested and qualified after a full-term pregnancy and during a scheduled C-section. Our processor is thorough in their screening and testing process to ensure patient safety.
Order Products by Product Code or Product Name
Name Code Size
Axolotl Cryo™ AC10 1.0 mL
Axolotl Cryo™ AC20 2.0 mL